• Supports sleep
        • Supports general immune health


A common name for this mushroom is Reishi in Japanese (this is what it's called in America) and Lingzhi in Chinese.


Ganoderma lucidum is considered the "mushroom of immortality." It is regarded as a tonic in Traditional Chinese Medicine. Traditionally, it was believed that shen tonics supported peace of mind, joy, the balance of emotions, optimism, sound sleep, and clarity of thought.


As a shen tonic, reishi has traditionally been used to replenish Qi, ease, and center the mind, increase resistance to fatigue, promote well-being, and support sleep.


The herb was considered ideal for calming restlessness and quieting a hyperactive mind.

Additionally to these traditional uses, recent research has focused on reishi mushrooms' ability to support the immune system and rejuvenate the body. This is in addition to their ability to function as stem cells.


There are many compounds found in Reishi extracts, including polysaccharides (such as beta glucans), peptidoglycans, and triterpenoid compounds (e.g., lucidenic acids).


Additionally, the mushroom contains low amounts of nucleosides (adenine, guanine, inosine, thymidine, and uracil), nucleotides (adenine, guanine, hypoxanthine, thymine, and uracil), and a neurotransmitter named GABA[1-3].


Brain function


  • Supports learning and memory[4,5]
  • Supports sleep[6–13]
  • Supports neurogenesis[5,14]
  • Upregulates neural progenitor cell (NPC) proliferation[5]
  • Supports brain mitochondrial function[4,15,16]
  • Supports nerve growth factor (NGF)[17]
  • Supports neuroprotective functions[14,17,18]
  • Supports brain antioxidant defenses[4,15,16]




  • Supports healthy behavioral and physiological responses to stress [5,8,12,16,21,30–35]


Gut microbiota


  • Supports the composition of the gut microbiota[20–27]
  • Supports microbial metabolism[21,26,28]
  • Supports gut immunity[21,27]
  • Supports intestinal barrier function[27]


Immune System


  • Supports general immune health[29–33]
  • Supports innate immunity[34–47]
  • Supports adaptive immunity[36–38,42,45,48–51]
  • Supports mucosal immunity[26,45,52,53]  
  • Supports immune tolerance[48,54–56]
  • Supports cellular intrinsic immune defenses[33,57–65]
  • Supports immune signaling[31,38,41]
  • Supports healthy dendritic cell function[35,41,46,66–69]
  • Supports healthy natural killer cell function[29,37–42,45–47,70,71]
  • Supports healthy macrophage function[39,47]
  • Supports healthy microglial function[72,73]
  • Supports healthy B cell function[49,74,75]
  • Supports healthy T cell function[38,39,41,70]


Healthy aging


  • Supports mitochondrial function[15,18]
  • Supports mitochondrial biogenesis[17]
  • Supports autophagy[18,76]
  • Supports AMPK signaling[18,77]
  • Supports mTOR signaling[18,76–78]
  • Supports stem cell proliferation[79,80]
  • Supports stem cell differentiation[81]
  • Supports antioxidant defenses[82]
  • Supports Nrf2[83–86]


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