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PHOSPHATIDYLSERINE (FROM SUNFLOWER LECITHIN) BENEFITS

KEY BENEFITS OF PHOSPHATIDYLSERINE

      • Supports a healthy stress response
      • Supports brain function and cognitive performance
      • Supports mood

ABOUT PHOSPHATIDYLSERINE

A dietary phospholipid is a phosphatidylserine. Meat and fish are the best sources. Vegans can get phosphatidylserine from lecithin and white beans.

 

Phosphatidylserine is found in the innermost layer of cells where it governs the functions and activities of receptors, enzymes, ion channels, and signal molecules.

 

In the human cerebral cortex, phosphatidylserine comprises 13% of the membrane phospholipids.

 

A phospholipid in the membrane, phosphatidylcholine, can be converted to phosphatidylserine from dietary choline or supplement ingredients such as alpha-GPC or citicoline.

 

Phosphatidylserine has mainly been investigated in relation to cognitive function, mood regulation, and stress regulation [1].


PHOSPHATIDYLSERINE FULL BENEFITS

Brain and cognitive function

 

  • Supports memory and learning [2–10]
  • Supports executive function [2]
  • Supports mental flexibility [2]
  • Supports attention [4]
  • Supports number processing and calculation [11]
  • Supports cognitive health [2,5,9,12–15]
  • Supports acetylcholine release [13,16–18]
  • Supports monoamine oxidase B (MAO-B) [19,20]
  • Supports brain-derived neurotrophic factor (BDNF) [12]
  • Supports hippocampal IGF levels [12]
  • Supports the HPA axis [21,22]
  • Supports brain glucose metabolism [23,24]
  • Supports healthy EEG parameters [25,26]

 

Mood

 

  • Supports positive affect [6,9]
  • Supports healthy stress responses [27]

 

Exercise performance (ergogenic effects)

 

  • Supports resistance to exhaustion [28]
  • Supports healthy stress responses to exercise [21,22]

 

Complementary ingredients

 

  • Ginkgo biloba in supporting memory [29]
  • DHA in supporting memory and cognitive health [30,31]

PHOSPHATIDYLSERINE CAN BE FOUND IN:

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REFERENCES

[1]H.-Y. Kim, B.X. Huang, A.A. Spector, Prog. Lipid Res. 56 (2014) 1–18.
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[3]A. Kato-Kataoka, M. Sakai, R. Ebina, C. Nonaka, T. Asano, T. Miyamori, J. Clin. Biochem. Nutr. 47 (2010) 246–255.
[4]S. Hirayama, K. Terasawa, R. Rabeler, T. Hirayama, T. Inoue, Y. Tatsumi, M. Purpura, R. Jäger, J. Hum. Nutr. Diet. 27 Suppl 2 (2014) 284–291.
[5]T. Cenacchi, T. Bertoldin, C. Farina, M.G. Fiori, G. Crepaldi, Aging 5 (1993) 123–133.
[6]M. Maggioni, G.B. Picotti, G.P. Bondiolotti, A. Panerai, T. Cenacchi, P. Nobile, F. Brambilla, Acta Psychiatr. Scand. 81 (1990) 265–270.
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[19]T.D. Buckman, S. Eiduson, R. Boscia, Biochem. Pharmacol. 32 (1983) 3639–3647.
[20]K.H. Tachiki, T.D. Buckman, S. Eiduson, A.S. Kling, J. Hullett, Biol. Psychiatry 21 (1986) 59–68.
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[23]P. Klinkhammer, B. Szelies, W.-D. Heiss, Dement. Geriatr. Cogn. Disord. 1 (1990) 197–201.
[24]W.-D. Heiss, J. Kessler, R. Mielke, B. Szelies, K. Herholz, Dement. Geriatr. Cogn. Disord. 5 (1994) 88–98.
[25]G. Rosadini, W.G. Sannita, F. Nobili, T. Cenacchi, Neuropsychobiology 24 (1990) 42–48.
[26]R.R. Engel, W. Satzger, W. Günther, N. Kathmann, D. Bove, S. Gerke, U. Münch, H. Hippius, Eur. Neuropsychopharmacol. 2 (1992) 149–155.
[27]J. Baumeister, T. Barthel, K.R. Geiss, M. Weiss, Nutr. Neurosci. 11 (2008) 103–110.
[28]M.I. Kingsley, M. Miller, L.P. Kilduff, J. McEneny, D. Benton, Med. Sci. Sports Exerc. 38 (2006) 64–71.
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[30]V. Vakhapova, T. Cohen, Y. Richter, Y. Herzog, A.D. Korczyn, Dement. Geriatr. Cogn. Disord. 29 (2010) 467–474.
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