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MUCUNA PRURIENS SEED BENEFITS

KEY BENEFITS OF MUCUNA PRURIENS

        • Supports neuroprotection
        • Supports antioxidant defenses
        • Supports brain function

ABOUT MUCUNA PRURIENS

Mucuna pruriens, also known as velvet bean, is a legume commonly used in Southeast Asia as a food source and as a medicine in traditional Indian systems of medicine.

 

Flavonoids, saponins, lectins, and alkaloids are present in M.pruriens seeds (i.e., the beans).

 

The beans contain a large amount of L-3,4-dihydroxyphenylalanine (L-DOPA), making them an excellent source of the amino acid.

 

Green beans and fava beans are other sources of L-DOPA. Because L-DOPA is a direct precursor of dopamine in the brain, M.pruriens has long been used as a nootropic for cognitive performance.

 

One of the major neurotransmitters in the brain is dopamine. Several important brain functions are affected by it, including reward, motivation, pleasure, focus, cognitive flexibility, emotional resilience, and motor control.

 

In order to function cognitively and emotionally well, dopamine signaling must be functioning properly [1–3].


MUCUNA PRURIENS FULL BENEFITS

Brain function

 

  • Supports dopamine levels and dopaminergic neurotransmission [3,5]
  • Supports noradrenaline levels [3,5]
  • Supports serotonin levels [3,5]
  • Supports cognitive health [6]
  • Supports neuroprotective functions [6–9]
  • Supports neural antioxidant defenses [10]
  • Counters neural ROS levels and oxidative stress [7,11]
  • Supports growth hormone levels [12]
  • Supports neural immune signaling [9,13,14]

 

Stress and mood

 

  • Supports healthy behavioral and physiological stress responses [9,15]
  • Supports healthy stress hormone levels [12,16]
  • Supports healthy behavioral responses [9,17]

 

General health

 

  • Supports healthy blood pressure [18,19]
  • Supports healthy blood glucose levels [20–22]
  • Supports mitochondrial function [5,23,24]
  • Supports antioxidant defenses [6,10,11,15,23,24]

 

Male reproductive health

 

  • Supports healthy testosterone levels [25,26]
  • Supports sperm count and motility [15,23–25,27]

MUCUNA PRURIENS SEED CAN BE FOUND IN:

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REFERENCES

[1]L.R. Lampariello, A. Cortelazzo, R. Guerranti, C. Sticozzi, G. Valacchi, Afr. J. Tradit. Complement. Altern. Med. 2 (2012) 331–339.

[2]H. Pulikkalpura, R. Kurup, P.J. Mathew, S. Baby, Sci. Rep. 5 (2015) 11078.

[3]P. De Deurwaerdère, G. Di Giovanni, M.J. Millan, Prog. Neurobiol. 151 (2017) 57–100.

[4]M. Rijntjes, Parkinson’s Disease 2019 (2019) 1–9.

[5]B.V. Manyam, M. Dhanasekaran, T.A. Hare, Phytother. Res. 18 (2004) 706–712.

[6]V.S. Nayak, N. Kumar, A.S. D’Souza, S.S. Nayak, S.P. Cheruku, K.S.R. Pai, Neuroreport 28 (2017) 1195–1201.

[7]S.L. Johnson, H.Y. Park, N.A. DaSilva, D.A. Vattem, H. Ma, N.P. Seeram, Nutrients 10 (2018).

[8]P. Concessao, L.K. Bairy, A.P. Raghavendra, Vet World 13 (2020) 1555–1566.

[9]R.L. Tavares, M.H.A. de Vasconcelos, M.L. da V. Dutra, A.B. D’Oliveira, M.D.S. Lima, M.G. da S.S. Salvadori, R. de A. Pereira, A.F. Alves, Y.M. do Nascimento, J.F. Tavares, O. Guzman-Quevedo, J. de S. Aquino, Molecules 25 (2020).

[10]S.K. Yadav, J. Prakash, S. Chouhan, S.P. Singh, Neurochem. Int. 62 (2013) 1039–1047.

[11]M. Dhanasekaran, B. Tharakan, B.V. Manyam, Phytother. Res. 22 (2008) 6–11.

[12]G. Boden, L.E. Lundy, O.E. Owen, Neuroendocrinology 10 (1972) 309–315.

[13]S.N. Rai, H. Birla, W. Zahra, S.S. Singh, S.P. Singh, J. Chem. Neuroanat. 85 (2017) 27–35.

[14]A. Rachsee, N. Chiranthanut, P. Kunnaja, S. Sireeratawong, P. Khonsung, S. Chansakaow, A. Panthong, J. Ethnopharmacol. 267 (2021) 113518.

[15]K.K. Shukla, A.A. Mahdi, M.K. Ahmad, S.P. Jaiswar, S.N. Shankwar, S.C. Tiwari, Evid. Based. Complement. Alternat. Med. 7 (2010) 137–144.

[16]T. Müller, J. Welnic, S. Muhlack, J. Neural Transm. 114 (2007) 347–350.

[17]D.G. Rana, V.J. Galani, Ayu 35 (2014) 90–97.

[18]L. Chel-Guerrero, S. Galicia-Martínez, J.J. Acevedo-Fernández, J. Santaolalla-Tapia, D. Betancur-Ancona, J. Med. Food 20 (2017) 37–45.

[19]M.Y. Khan, V. Kumar, J. Complement. Integr. Med. 14 (2017).

[20]S.O. Majekodunmi, A.A. Oyagbemi, S. Umukoro, O.A. Odeku, Asian Pac. J. Trop. Med. 4 (2011) 632–636.

[21]S.S. Rathi, J.K. Grover, V. Vats, Phytother. Res. 16 (2002) 236–243.

[22]A. Bhaskar, V.G. Vidhya, M. Ramya, Fitoterapia 79 (2008) 539–543.

[23]S. Suresh, E. Prithiviraj, N.V. Lakshmi, M.K. Ganesh, L. Ganesh, S. Prakash, J. Ethnopharmacol. 145 (2013) 32–41.

[24]A.P. Singh, S. Sarkar, M. Tripathi, S. Rajender, PLoS One 8 (2013) e54655.

[25]K.K. Shukla, A.A. Mahdi, M.K. Ahmad, S.N. Shankhwar, S. Rajender, S.P. Jaiswar, Fertil. Steril. 92 (2009) 1934–1940.

[26]S. Suresh, S. Prakash, J. Sex. Med. 9 (2012) 3066–3078.

[27]M.K. Ahmad, A.A. Mahdi, K.K. Shukla, N. Islam, S.P. Jaiswar, S. Ahmad, Fertil. Steril. 90 (2008) 627–635.