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- Supports brain function
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Supports vision
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Supports mood
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Supports vision
Supports mood
Lucitex® 2020 is an award-winning extract of marigold flowers that contains lutein, zeaxanthin, and mesozeaxanthin, three macular carotenoids.
Carotenoids are divided into two groups. Carotene (beta-carotene) is one of the groups. A second group is xanthophylls.
Lutein, zeaxanthin, and meso-zeaxanthin are yellow-colored xanthophylls. Xanthophylls are classified as xanthophylls because of chemical properties that allow them to cross both the blood-brain barrier and the blood-retina barrier (beta-carotene, as an example, cannot cross either), and this makes them excellent antioxidants.
Vegetables such as green leafy vegetables are the best sources of lutein.
The Goji fruit is one of the best sources of zeaxanthin.
Lucien zeaxanthin, and meso-zeaxanthin are termed macular carotenoids (or macular pigments) because they accumulate in the macula, the region of the retina that provides sharp, clear central vision. This region appears yellow because of these macular carotenoids.
Lutein, zeaxanthin, and meso-zeaxanthin play a crucial role in filtering blue light from entering the eye and serving as a kind of shade for the macula, which is one of the reasons why they are so important for the health of the eye and visual system.
The brain is also abundant with lutein and zeaxanthin (along with cryptoxanthin), where lutein alone accounts for more than one-third of the brain's carotenoids.
Studies have linked higher levels of lutein and zeaxanthin to healthy cognitive function [1–5].
Vision
Supports macular pigment levels [7–17]
Supports visual function [8–11,13,16–20]
Supports retinal function [20,21]
Supports resistance to eye strain [17]
Supports resistance to visual fatigue [17,22]
Supports photostress recovery [16]
Brain function
Supports cognitive performance [23]
Supports memory [15,23,24]
Supports sustained and complex attention [12,15,23]
Supports executive function [15]
Supports reasoning ability [12]
Supports cognitive flexibility [15]
Supports psychomotor speed [23]
Supports processing speed [23]
Supports neural visual-spatial processing [25]
Supports visual processing [13,14]
Supports spatial memory [12]
Supports brain activation [26]
Supports sleep quality [17]
Supports brain-derived neurotrophic factor (BDNF) levels [23]
Mood
Supports stress responses [27]
Supports emotional health [27]
General health
Supports blood antioxidant capacity [23]
Influences blood cytokine levels [23]
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[2]P.S. Bernstein, B. Li, P.P. Vachali, A. Gorusupudi, R. Shyam, B.S. Henriksen, J.M. Nolan, Prog. Retin. Eye Res. 50 (2016) 34–66.
[3]L.H. Li, J.C.-Y. Lee, H.H. Leung, W.C. Lam, Z. Fu, A.C.Y. Lo, Nutrients 12 (2020).
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[5]E.J. Johnson, Nutr. Rev. 72 (2014) 605–612.
[6]D.I. Thurnham, Nutrition Research Reviews 20 (2007) 163–179.
[7]A. Obana, Y. Gohto, R. Nakazawa, T. Moriyama, W. Gellermann, P.S. Bernstein, Sci. Rep. 10 (2020) 10262.
[8]N. Machida, M. Kosehira, N. Kitaichi, Nutrients 12 (2020).
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[10]J.M. Nolan, R. Power, J. Stringham, J. Dennison, J. Stack, D. Kelly, R. Moran, K.O. Akuffo, L. Corcoran, S. Beatty, Invest. Ophthalmol. Vis. Sci. 57 (2016) 3429–3439.
[11]J.M. Nolan, J. Loughman, M.C. Akkali, J. Stack, G. Scanlon, P. Davison, S. Beatty, Vision Res. 51 (2011) 459–469.
[12]L.M. Renzi-Hammond, E.R. Bovier, L.M. Fletcher, L.S. Miller, C.M. Mewborn, C.A. Lindbergh, J.H. Baxter, B.R. Hammond, Nutrients 9 (2017).
[13]E.R. Bovier, L.M. Renzi, B.R. Hammond, PLoS One 9 (2014) e108178.
[14]E.R. Bovier, B.R. Hammond, Arch. Biochem. Biophys. 572 (2015) 54–57.
[15]B.R. Hammond Jr, L.S. Miller, M.O. Bello, C.A. Lindbergh, C. Mewborn, L.M. Renzi-Hammond, Front. Aging Neurosci. 9 (2017) 254.
[16]J.M. Stringham, K.J. O’Brien, N.T. Stringham, Eye Vis (Lond) 3 (2016) 30.
[17]J.M. Stringham, N.T. Stringham, K.J. O’Brien, Foods 6 (2017).
[18]L. Ma, X.-M. Lin, Z.-Y. Zou, X.-R. Xu, Y. Li, R. Xu, Br. J. Nutr. 102 (2009) 186–190.
[19]J. Kvansakul, M. Rodriguez-Carmona, D.F. Edgar, F.M. Barker, W. Köpcke, W. Schalch, J.L. Barbur, Ophthalmic Physiol. Opt. 26 (2006) 362–371.
[20]R. Liu, T. Wang, B. Zhang, L. Qin, C. Wu, Q. Li, L. Ma, Invest. Ophthalmol. Vis. Sci. 56 (2014) 252–258.
[21]Age-Related Eye Disease Study 2 (AREDS2) Research Group, E.Y. Chew, T.E. Clemons, J.P. Sangiovanni, R.P. Danis, F.L. Ferris 3rd, M.J. Elman, A.N. Antoszyk, A.J. Ruby, D. Orth, S.B. Bressler, G.E. Fish, G.B. Hubbard, M.L. Klein, S.R. Chandra, B.A. Blodi, A. Domalpally, T. Friberg, W.T. Wong, P.J. Rosenfeld, E. Agrón, C.A. Toth, P.S. Bernstein, R.D. Sperduto, JAMA Ophthalmol. 132 (2014) 142–149.
[22]A. Yagi, K. Fujimoto, K. Michihiro, B. Goh, D. Tsi, H. Nagai, Appl. Ergon. 40 (2009) 1047–1054.
[23]N.T. Stringham, P.V. Holmes, J.M. Stringham, Physiol. Behav. 211 (2019) 112650.
[24]R. Power, R.F. Coen, S. Beatty, R. Mulcahy, R. Moran, J. Stack, A.N. Howard, J.M. Nolan, J. Alzheimers. Dis. 61 (2018) 947–961.
[25]C.M. Mewborn, C.A. Lindbergh, T.L. Robinson, M.A. Gogniat, D.P. Terry, K.R. Jean, B.R. Hammond, L.M. Renzi-Hammond, L.S. Miller, Nutrients 10 (2018).
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[27]N.T. Stringham, P.V. Holmes, J.M. Stringham, Nutr. Neurosci. 21 (2018) 286–296.
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