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LACTOCOCCUS LACTIS STRAIN PLASMA (HEAT KILLED) BENEFITS

KEY BENEFITS OF LACTOCOCCUS LACTIS STRAIN PLASMA (HEAT KILLED)

    • Supports upper respiratory tract health
    • Supports general immune health
    • Supports healthy immune function after intense exercise
    • Supports mucosal immune health

ABOUT LACTOCOCCUS LACTIS STRAIN PLASMA (HEAT KILLED)

Kirin Holdings Co, Ltd. developed Lactococcus lactis strain Plasma (heat-killed) as a clinically researched probiotic. Heat-killed Lactococcus lactis JCM 5805 is sometimes called LC-Plasma and other times LC-Plasma in clinical studies.

 

The first part of the name (e.g. Lactococcus) indicates the genus. The second part (e.g. lactis) indicates the species. Lastly, the third part of the name (for example, "Plasma" or "JCM 5805") describes the strain.

 

Special strains of L.lactis support the immune system specifically.

 

The heated strain of Lactococcus lactis is both paraprobiotic and immunobiotic.

 

Heat-treated paraprobiotics are the subcategory of probiotics. In contrast, to live probiotics, paraprobiotics are inactivated and do not need to be refrigerated.

 

An immunobiotic is a type of probiotic that supports a healthy immune system. L. lacticis strain Plasma is inactivated, and, because of this, does not require refrigeration, and possesses an immunobiotic action unmatched by any other lactic acid bacteria (alive or inactivated).

 

The immune system is comprised of many interacting white blood cells (also known as immune cells). Plasmacytoid dendritic cells (pDCs) are a rare immune cell type found exclusively in L.lactis strains.

 

Because they organize and direct many other immune cells, PDCS have been described as a leader of the immune system. Human studies have demonstrated that Lactococcus lactis strain Plasma (heat-killed) supports healthy working days and immunity during periods of high-intensity exercise.


LACTOCOCCUS LACTIS STRAIN PLASMA (HEAT KILLED) FULL BENEFITS

Immune function

 

  • Supports brain protein synthesis [23–26]
  • Supports general immune health[1–4]
  • Supports post-exercise immunity[5,6]
  • Supports innate immunity[2,4,5,7–10]
  • Supports adaptive immunity[4,11,12]
  • Supports GI mucosal immunity[4,13]
  • Supports skin mucosal immunity[14]
  • Supports cellular intrinsic immune defenses[13,15]
  • Supports healthy plasmacytoid dendritic cell (pDC) function[2,5,7–11,13,14,16,17]
  • Supports healthy natural killer cell function[10]
  • Supports healthy neutrophil function[4]
  • Supports healthy T cell function[11,12]
  • Supports healthy B cell function[4,11]

 

Exercise

 

  • May help support recovery from fatigue produced by high-intensity exercise[5]

 

Healthy aging

 

  • Supports healthspan (mice)[16]
  • Supports against cellular senescence[12,16]

LACTOCOCCUS LACTIS STRAIN PLASMA CAN BE FOUND IN:

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REFERENCES

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[2] T. Shibata, M. Kanayama, M. Haida, S. Fujimoto, T. Oroguchi, K. Sata, N. Mita, T. Kutsuzawa, M. Ikeuchi, M. Kondo, K. Naito, M. Tsuda, Y. Nishizaki, N. Ishii, J. Funct. Foods 24 (2016) 492–500.
[3] K. Sakata, Y. Sasaki, K. Jounai, T. Fujii, D. Fujiwara, Health 09 (2017) 756–762.
[4] T. Fujii, K. Jounai, A. Horie, H. Takahashi, H. Suzuki, K. Ohshio, D. Fujiwara, N. Yamamoto, J. Funct. Foods 35 (2017) 513–521.
[5] Y. Komano, K. Shimada, H. Naito, K. Fukao, Y. Ishihara, T. Fujii, T. Kokubo, H. Daida, J. Int. Soc. Sports Nutr. 15 (2018) 39.
[6] T. Kokubo, Y. Komano, R. Tsuji, D. Fujiwara, T. Fujii, O. Kanauchi, International Journal of Sport Nutrition and Exercise Metabolism (2019) 1–5.
[7] T. Sugimura, K. Jounai, K. Ohshio, T. Tanaka, M. Suwa, D. Fujiwara, Clin. Immunol. 149 (2013) 509–518.
[8] K. Jounai, K. Ikado, T. Sugimura, Y. Ano, J. Braun, D. Fujiwara, PLoS One 7 (2012) e32588.
[9] K. Jounai, T. Sugimura, K. Ohshio, D. Fujiwara, PLoS One 10 (2015) e0119055.
[10] H. Suzuki, K. Ohshio, D. Fujiwara, Biosci. Biotechnol. Biochem. 80 (2016) 798–800.
[11] H. Suzuki, K. Jounai, K. Ohshio, T. Fujii, D. Fujiwara, Biochem. Biophys. Res. Commun. 503 (2018) 1315–1321.
[12] R. Tsuji, Y. Komano, K. Ohshio, N. Ishii, O. Kanauchi, Exp. Gerontol. 111 (2018) 10–16.
[13] K. Jounai, T. Sugimura, Y. Morita, K. Ohshio, D. Fujiwara, Int. Immunopharmacol. 56 (2018) 205–211.
[14] R. Tsuji, T. Fujii, Y. Nakamura, K. Yazawa, O. Kanauchi, J. Infect. Dis. 220 (2019) 892–901.
[15] H. Suzuki, R. Tsuji, M. Sugamata, N. Yamamoto, N. Yamamoto, O. Kanauchi, Int. J. Mol. Med. 43 (2019) 426–434.
[16] T. Sugimura, K. Jounai, K. Ohshio, H. Suzuki, T. Kirisako, Y. Sugihara, D. Fujiwara, Int. Immunopharmacol. 58 (2018) 166–172.[17] T. Sugimura, K. Jounai, K. Ohshio, D. Fujiwara, Biosci. Biotechnol. Biochem. 83 (2019) 2140–2143.