• Supports mood
    • Supports neuroprotection
    • Supports vascular function
    • Supports brain health and cognitive performance


One of the most widely used and researched herbs for the brain is Ginkgo biloba. Traditional Chinese Medicine has used ginkgo biloba for several hundred years. The use of standardized Ginkgo biloba extracts dates back to the mid-1960s.


As the only surviving species of the order Ginkgoales that existed on earth 190 million years ago, the Ginkgo biloba tree is a living fossil native to China. Some specimens of the trees are believed to be as old as 1,500 years.


Some of its bioactive ingredients include flavonoid glycosides such as quercetin, kaempferol, and isorhamnetin, as well as substances known as terpene lactones such as ginkgolides A, B, and C, and bilobalide. These compounds in Ginkgo are responsible for supporting multiple neurotransmitter systems, supporting neurogenesis, as well as supporting healthy vascular function and cerebral blood flow.


One of the best-known effects of Ginkgo Biloba is its ability to promote attention, concentration, memory, and mood.


Brain and cognitive function


  • Supports memory [2–6]
  • Supports working memory [3,7,8]
  • Supports attention [9,10]
  • Supports information processing speed [7,11]
  • Supports executive function [7]
  • Supports cognitive health [12–14]
  • Supports healthy cerebral blood flow [15–17]
  • Supports acetylcholine levels [18]
  • Influences anticholinesterase activity [19]
  • Supports dopamine levels [20,21]
  • Supports noradrenaline levels [20]
  • Supports serotonergic neurotransmission [22–24]
  • Supports neurogenesis [25–27]
  • Supports synaptogenesis [25]
  • Supports brain-derived neurotrophic factor (BDNF) [24,25,28,29]
  • Supports cyclic-AMP response element binding protein (CREB) activity [26]
  • Supports neuronal membrane fluidity [30]
  • Supports neuroprotective functions [31–35]


Mood and stress response


  • Supports a calm mood and positive affect [24,36–39]
  • Supports healthy stress responses and stress hormone levels (adaptogenic) [40,41]
  • Modulates the hypothalamic-pituitary-adrenal (HPA) axis [42]


Vascular health


  • Supports healthy blood flow [43–46]
  • Supports endothelial function [47–51]
  • Supports vascular function [52–54]
  • Influences platelet-activating factor (PAF) activity [55–57]
  • Supports blood antioxidant capacity [29]


Healthy aging and longevity


  • Supports antioxidant defenses [22–24]
  • Counters ROS production and oxidative stress [22–25]
  • Supports free radical scavenging [25,26]
  • Supports mitochondrial function [47,50,58–60]
  • Supports mitochondrial responses to age-related oxidative stress [61]


Complementary ingredients


  • Ginger for mood support [62–65]
  • Ginseng for cognitive performance [66–71]
  • Rhodiola for cognitive performance [72]


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