• Supports healthy vision
    • Supports brain health


Among the omega-3 fatty acids (or n*3 fatty acids), docosahexaenoic acid (DHA) is one of the main three. The other two are alpha-linolenic acid (ALA) and eicosapentaenoic acid (EPA).


Among omega-3 fatty acids, DHA is the most abundant in the brain, where it occupies a central role in the membrane of neuronal cells and helps to facilitate cell signaling [1].


The retina also contains high levels of DHA, which contributes to healthy vision.


It is true that DHA can be produced in the body through the conversion of its precursor *-linolenic acid (ALA), but this only occurs in a limited amount. Diet is the main source of DHA.


The best food source of DHA (and EPA) is cold-water fish. DHA is mostly derived from the microalgae that fish consume. A vegan or vegetarian can increase their dietary intake of DHA without consuming fish or other animal products by taking DHA from algae, which eliminates the middleman.


Neuronal structure


  • DHA is an omega-3 fatty acid found in cell membrane phospholipids [1]
  • DHA is the main structural component of the neuronal cell membrane [1]
  • Supports synaptic neuronal membrane fluidity [4]
  • Supports neuronal (dendritic) structure [5]


Brain function and cognition


  • Supports brain phospholipid levels [6]
  • Supports dopamine signaling [7]
  • Supports serotonin signaling [7]
  • Supports the HPA axis [7]
  • Supports neuronal choline uptake via the high-affinity choline uptake system [8]
  • Supports memory and learning [9–12]
  • Supports working memory [13]
  • Supports reaction time [13]
  • Supports cognitive health [9,11,12]
  • Supports neuroprotective functions [4,11,12,14]
  • Supports brain antioxidant defenses [11,12]




  • Supports a calm mood and healthy stress responses [15–18]
  • Supports positive affective responses [7]


Heart health


  • Supports healthy blood triglyceride levels [19,20]
  • Supports healthy blood cholesterol levels [19,20]




  1. Supports AMP-Activated Protein Kinase (AMPK) activity [21,22]
  2. Supports SIRT-1 activity [21]
  3. Influences mTOR activity [22]
  4. Supports autophagy [22]


Complementary ingredients


  • Uridine in supporting memory, dendritic spine density, synaptic protein levels, and phospholipids in the brain [6,23–26]
  • Phosphatidylserine in supporting memory and cognitive health [27,28]



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[1]L. Lauritzen, H.S. Hansen, M.H. Jørgensen, K.F. Michaelsen, Prog. Lipid Res. 40 (2001) 1–94.
[2]H. Brault, D. Miketinas, Curr Dev Nutr 3 (2019).
[3]T.A.B. Sanders, Prostaglandins Leukot. Essent. Fatty Acids 81 (2009) 137–141.
[4]M. Hashimoto, S. Hossain, T. Shimada, O. Shido, Clin. Exp. Pharmacol. Physiol. 33 (2006) 934–939.
[5]F. Calon, G.P. Lim, F. Yang, T. Morihara, B. Teter, O. Ubeda, P. Rostaing, A. Triller, N. Salem Jr, K.H. Ashe, S.A. Frautschy, G.M. Cole, Neuron 43 (2004) 633–645.
[6]R.J. Wurtman, I.H. Ulus, M. Cansev, C.J. Watkins, L. Wang, G. Marzloff, Brain Res. 1088 (2006) 83–92.
[7]L.-H. Jiang, Q.-Y. Liang, Y. Shi, Eur. Rev. Med. Pharmacol. Sci. 16 (2012) 1765–1773.
[8]B.T. Hyman, A.A. Spector, J. Neurochem. 38 (1982) 650–656.
[9]K. Yurko-Mauro, D. McCarthy, D. Rom, E.B. Nelson, A.S. Ryan, A. Blackwell, N. Salem Jr, M. Stedman, MIDAS Investigators, Alzheimers. Dement. 6 (2010) 456–464.
[10]S. Gamoh, M. Hashimoto, K. Sugioka, M. Shahdat Hossain, N. Hata, Y. Misawa, S. Masumura, Neuroscience 93 (1999) 237–241.
[11]M. Hashimoto, Y. Tanabe, Y. Fujii, T. Kikuta, H. Shibata, O. Shido, J. Nutr. 135 (2005) 549–555.
[12]M. Hashimoto, S. Hossain, T. Shimada, K. Sugioka, H. Yamasaki, Y. Fujii, Y. Ishibashi, J.-I. Oka, O. Shido, J. Neurochem. 81 (2002) 1084–1091.
[13]W. Stonehouse, C.A. Conlon, J. Podd, S.R. Hill, A.M. Minihane, C. Haskell, D. Kennedy, Am. J. Clin. Nutr. 97 (2013) 1134–1143.
[14]K. Mayurasakorn, J.J. Williams, V.S. Ten, R.J. Deckelbaum, Curr. Opin. Clin. Nutr. Metab. Care 14 (2011) 158–167.
[15]T. Hamazaki, M. Itomura, S. Sawazaki, Y. Nagao, Biofactors 13 (2000) 41–45.
[16]T. Hamazaki, S. Sawazaki, T. Nagasawa, Y. Nagao, Y. Kanagawa, K. Yazawa, Lipids 34 Suppl (1999) S33–7.
[17]S. Sawazaki, T. Hamazaki, K. Yazawa, M. Kobayashi, J. Nutr. Sci. Vitaminol. 45 (1999) 655–665.
[18]T. Takeuchi, M. Iwanaga, E. Harada, Brain Res. 964 (2003) 136–143.
[19]M.Y. Wei, T.A. Jacobson, Curr. Atheroscler. Rep. 13 (2011) 474–483.
[20]A.M. Bernstein, E.L. Ding, W.C. Willett, E.B. Rimm, J. Nutr. 142 (2012) 99–104.
[21]B. Xue, Z. Yang, X. Wang, H. Shi, PLoS One 7 (2012) e45990.
[22]K. Jing, K.-S. Song, S. Shin, N. Kim, S. Jeong, H.-R. Oh, J.-H. Park, K.-S. Seo, J.-Y. Heo, J. Han, J.-I. Park, C. Han, T. Wu, G.-R. Kweon, S.-K. Park, W.-H. Yoon, B.-D. Hwang, K. Lim, Autophagy 7 (2011) 1348–1358.
[23]S. Holguin, Y. Huang, J. Liu, R. Wurtman, Behav. Brain Res. 191 (2008) 11–16.
[24]S. Holguin, J. Martinez, C. Chow, R. Wurtman, FASEB J. 22 (2008) 3938–3946.
[25]T. Sakamoto, M. Cansev, R.J. Wurtman, Brain Res. 1182 (2007) 50–59.
[26]M. Cansev, R.J. Wurtman, Neuroscience 148 (2007) 421–431.
[27]V. Vakhapova, T. Cohen, Y. Richter, Y. Herzog, A.D. Korczyn, Dement. Geriatr. Cogn. Disord. 29 (2010) 467–474.
[28]Y. Richter, Y. Herzog, T. Cohen, Y. Steinhart, Clin. Interv. Aging 5 (2010) 313–316.