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BROCCOLI SPROUTs

TOP BENEFITS OF BROCCOLI SPROUTS

    • Supports general immune health*
    • Supports antioxidant defenses*
    • Supports detoxification functions*

WHAT ARE BROCCOLI SPROUTS?

Broccoli sprouts (botanical name Brassica oleracea italica) are the first green shoots, emerging within several days after a broccoli seed has been germinated (i.e., sprouted). They are often described as being a superfood because they are high in fiber, protein, and other nutrients. Broccoli sprouts are known for being one of the richest sources of glucosinolates, especially glucoraphanin, the precursor to sulforaphane. These glucosinolate compounds are examples of plant defense compounds, which are produced by broccoli seeds and sprouts to better prepare them to respond to environmental stress. When humans consume broccoli sprouts, it’s thought that some of this stress-resilience is conferred. In other words, broccoli sprouts signal our cells to adapt in ways that support their defenses against stress. Sulforaphane has been the most studied of the glucosinolates. It is an Nrf2 activator—Nrf2 is a master regulator of cellular defenses and plays a role in supporting a healthy immune system.

BROCCOLI SPROUTS KEY MECHANISMS

Cellular defenses

 

  • Supports Nrf-2 signaling [2–6]

  • Supports antioxidant defenses [7–12]

  • Supports detoxification functions [13,14]

  • Supports phase II detoxification enzymes (e.g., NQO1, GST, and HO1) [15–18]

 

Immunity

 

  • Supports general immune health [19–22]

  • Supports innate immunity [2,20,22–29]

  • Supports adaptive immunity [2,23,26,28,30–34]

  • Supports cellular intrinsic immune defenses [32,35–41]

  • Supports mucosal immunity [3,34,42]

  • Supports immune tolerance [33,43–47]

  • Supports immune signaling [23,30,33,48]

  • Supports healthy dendritic cell function [2,48]

  • Supports healthy natural killer (NK) cell function [11,20,23,28]

  • Supports healthy macrophage function [22,24–29]

  • Supports healthy microglial function [4,49–55]

  • Supports healthy T cell function [2,30–33]

  • Supports healthy B cell function [23,26,34]

  • Supports immunity during aging [2]

     

 

Gut microbiota

 

  • Supports a healthy gut microbiota [34]

  • Supports gut microbial metabolism [34]

 

Healthy aging

 

  • Supports histone deacetylase inhibition [56,57]

  • Supports Nrf2 [58–63]

  • Supports liver function [64]

  • Supports metabolic health [65]

  • Slows cellular senescence [66,67]

  • Supports mitochondrial function [68–80]

 

Brain and mood

 

  • Supports cognitive wellness [81,82]

  • Supports brain-derived neurotrophic factor (BDNF) [83,84]

     

  • Supports social cognition [85]

  • Supports healthy behavioral and cognitive responses to stress [86,87]

 

Complementary ingredients

 

  • N-Acetyl-L-cysteine in support of cellular antioxidant defenses [88–90]

  • Curmcumin in support of cellular defenses and immune signaling [91]

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