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BIOTIN BENEFITS

KEY BENEFITS OF BIOTIN

      • Supports gene expression
      • Supports cellular metabolic pathways


ABOUT BIOTIN

The water-soluble vitamin B7, biotin, contributes to cellular metabolism and energy production. It is part of the B complex.

 

Vitamin H was originally called Biotin, where "H" stood for Haar und Haut, German words for hair and skin. Because skin rash and thinning hair were some of the symptoms of biotin deficiency that led to its eventual discovery.

 

Some people have difficulty maintaining adequate levels of biotin due to factors such as diet, lifestyle, and genetics. Therefore, certain subsets of the population have more difficulty maintaining adequate levels of biotin.

 

As an essential cofactor, biotin is involved in fat and carbohydrate metabolism, cell growth, and protein synthesis.*


BIOTIN FULL BENEFITS

  • Biotin is required for the activity of acetyl-CoA carboxylase 1 (ACC1) and ACC2, pyruvate carboxylase, methylcrotonyl-CoA carboxylase, and propionyl-CoA carboxylase [2–4]

  • Biotin-dependent enzymes have important roles in pathways associated with gluconeogenesis, lipid catabolism, and

  • branched chain amino acid catabolism [2–4]

  • Biotin regulates chromatin structure and gene expression [2,3]

 

Skin health*

 

  • Supports nail structure and health [5–7]
  • Supports hair health [8]
  • Supports skin zinc homeostasis [9]

BIOTIN CAN BE FOUND IN:

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REFERENCES

[1]F. Saleem, M.P. Soos, in: StatPearls, StatPearls Publishing, Treasure Island (FL), 2021.

[2]L. Riveron-Negrete, C. Fernandez-Mejia, Mini Rev. Med. Chem. 17 (2017) 529–540.

[3]D.M. Mock, J. Nutr. 147 (2017) 1487–1492.

[4]L. Tong, Cell. Mol. Life Sci. 70 (2013) 863–891.

[5]V.E. Colombo, F. Gerber, M. Bronhofer, G.L. Floersheim, J. Am. Acad. Dermatol. 23 (1990) 1127–1132.

[6]G.L. Floersheim, Z. Hautkr. 64 (1989) 41–48.

[7]L.G. Hochman, R.K. Scher, M.S. Meyerson, Cutis 51 (1993) 303–305.

[8]D.P. Patel, S.M. Swink, L. Castelo-Soccio, Skin Appendage Disord 3 (2017) 166–169.

[9]Y. Ogawa, M. Kinoshita, T. Sato, S. Shimada, T. Kawamura, Nutrients 11 (2019).