• Supports sexual health
  • Supports muscle strength and endurance
  • Supports stress relief
  • Supports a healthy body weight
  • Supports sleep
  • Supports memory and cognition
  • Supports thyroid health


Ashwagandha is commonly known as Withania somnifera. Ashwagandha (or Indian ginseng) is considered a Rasayana—a type of elixir or tonic herb prized by the branch of Ayurvedic medicine devoted to rejuvenation and to promoting physical and mental well-being as one ages.


Ashwagandha occupies a prominent place among the Rasayana herbs, where it was used as a general tonic as well as an infusion of energy when ill-health or exhaustion was present.


Ashwagandha's key characteristic is that it promotes balance. In English, Indian ginseng was believed to share some of the same attributes as ashwagandha, taking care of the body in numerous ways, particularly when subjected to increased stress.


Adaptogens are plants that produce these types of nonspecific resistance and recovery from stress in addition to supporting general health, healthy energy, and homeostasis.


Ashwagandha has been shown to support sleep quality, relaxation, muscle recovery, cognitive function, immunity and a healthier stress response, among other benefits.




  • Supports sleep onset[1,2]

  • Supports sleep efficiency[1]

  • Supports quality of sleep[1,3]

  • Supports slow-wave sleep[2]

  • Supports total sleep time[2]


Mood and stress


  • Supports a calm mood[1,4]

  • Supports stress management[5–7]

  • Supports health cortisol levels[5–7]


Brain function


  • Supports cognitive and psychomotor performance[8,9]

  • Supports memory, executive function, attention, and information processing speed[10]

  • Supports GABAergic neurotransmission[2,11]

  • Supports GABA receptor signaling[12–14]

  • Supports dopamine levels[15]

  • Downregulates the basal activity levels of acetylcholine esterase[15]

  • Supports neuroprotection – protects from neuronal mitochondrial swelling and apoptosis; protects cognitive function (ischemia, oxidative stress)[16]

  • Protects from neurotoxicity[15,17]


Immune system


  • Supports innate immunity[18–22]

  • Supports adaptive immunity[18,19,22–31]

  • Supports immune system communication[22,32–34]


Mitochondrial function


  • Supports mitochondrial membrane potential and structural integrity[16]

  • Protects from mitochondrial damage[16]

  • Protects from mitochondrial membrane permeabilization[35]

  • Protects from complex I-V Inhibition (protects electron transport chain and oxidative phosphorylation performance)[15–



Exercise and sports


  • Supports endurance performance[37,38]

  • Supports muscle strength[39,40]

  • Supports post-exercise recovery[40]


Antioxidant defenses


  • Supports antioxidant enzymes (superoxide dismutase [SOD], catalase [CAT],glutathione peroxidase [GPx])[15–17,45,46]

  • Replenishes glutathione (GSH) levels[15,16,45]

  • Counters oxidative stress and reactive oxygen species levels[15,16,35,47]


Cellular signaling


  • Downregulates the expression of some cytokines including tumor necrosis factor alpha(TNFα), interleukin 1 beta (IL-1β), and IL-6[4,41,42]


Thyroid function


  • Supports thyroid function[48–50]


Healthy aging and longevity


  • Lifespan extension effects (Caenorhabditis elegans)[47,51]

  • Upregulates insulin-like growth factor-1 (IGF-1) signaling pathway[47,51]

  • Downregulates α-synuclein and amyloid-β aggregation[47]

  • Upregulates FOXO3A and SIRT3[52]


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