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ARTICHOKE STEM AND LEAF EXTRACT BENEFITS

KEY BENEFITS OF ARTICHOKE EXTRACT:

    • Supports vascular health
    • Supports antioxidant defenses
    • Supports metabolic health

KEY BENEFITS OF ARTICHOKE EXTRACT

Mediterranean artichokes (Cynara scolymus) are native to North Africa and Southern Europe and are renowned for their nutritional value and health benefits. Furthermore, artichoke leaves (called "bracts") also possess cell-protective qualities - the artichoke has the highest antioxidant capacity among all vegetables [1].

 

A group of compounds called anthocyanidins (cyanidin, peonidin, and delphinidin) is found in artichokes, including caffeine, quinic acid, cynarin, and chlorogenic acid.

 

The benefits of artichoke extract for health conditions such as heart health, metabolism, gastrointestinal health, and liver health have been demonstrated in clinical studies [2]. Among biohackers, artichokes are believed to have cognitive-enhancing properties, especially in the areas of motivation, mood, and memory.


ARTICHOKE EXTRACT FULL BENEFITS

Heart and vascular health

 

  • Supports healthy vascular function [3–7]

  • Supports endothelial cell function [5,7–10]

  • Supports endothelial nitric oxide synthase (eNOS) and NO production [5,7,8]

  • Supports healthy blood cholesterol levels [4,9,11–15]

  • Supports blood flow [9]

  • Supports antioxidant defenses [1,7,10,16]

  • Supports healthy LDL particles (may help counter LDL oxidation) [17]

 

Metabolism

 

  • Supports healthy blood glucose levels [14,18,19]

  • Supports healthy insulin signaling [20]

 

Other effects

 

  • May support flow through the cAMP>Creb>BDNF pathway by influencing phosphodiesterase (PDE4) [luteolin] [21]

  • Supports liver structure and function [3,15]

 

Complementary ingredients

 

  • Artichoke Leaf Extract is often combined with Coleus forskohlii (a source of forskolin) by neurohackers

 

ARTICHOKE STEM AND LEAF EXTRACT CAN BE FOUND IN:

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REFERENCES

[1]N. Ceccarelli, M. Curadi, P. Picciarelli, L. Martelloni, C. Sbrana, M. Giovannetti, Med. J. Nutrition Metab. 3 (2010) 197–201.
[2]M. Ben Salem, H. Affes, K. Ksouda, R. Dhouibi, Z. Sahnoun, S. Hammami, K.M. Zeghal, Plant Foods Hum. Nutr. 70 (2015) 441–453.
[3]K. Kraft, Phytomedicine 4 (1997) 369–378.
[4]W. Englisch, C. Beckers, M. Unkauf, M. Ruepp, V. Zinserling, Arzneimittelforschung 50 (2000) 260–265.
[5]S. Grande, P. Bogani, A. de Saizieu, G. Schueler, C. Galli, F. Visioli, J. Agric. Food Chem. 52 (2004) 5021–5026.
[6]N. Xia, A. Pautz, U. Wollscheid, G. Reifenberg, U. Förstermann, H. Li, Molecules 19 (2014) 3654–3668.
[7]I. D’Antuono, A. Carola, L.M. Sena, V. Linsalata, A. Cardinali, A.F. Logrieco, M.G. Colucci, F. Apone, Molecules 23 (2018).
[8]H. Li, N. Xia, I. Brausch, Y. Yao, U. Förstermann, J. Pharmacol. Exp. Ther. 310 (2004) 926–932.
[9]G. Lupattelli, S. Marchesi, R. Lombardini, A.R. Roscini, F. Trinca, F. Gemelli, G. Vaudo, E. Mannarino, Life Sci. 76 (2004) 775–782.
[10]D. Zapolska-Downar, A. Zapolski-Downar, M. Naruszewicz, A. Siennicka, B. Krasnodebska, B. Kołdziej, Life Sci. 71 (2002) 2897–2808.
[11]R. Bundy, A.F. Walker, R.W. Middleton, C. Wallis, H.C.R. Simpson, Phytomedicine 15 (2008) 668–675.
[12]Z. Qiang, S.-O. Lee, Z. Ye, X. Wu, S. Hendrich, Phytother. Res. 26 (2012) 1048–1052.
[13]M. Rondanelli, A. Giacosa, A. Opizzi, M.A. Faliva, P. Sala, S. Perna, A. Riva, P. Morazzoni, E. Bombardelli, Int. J. Food Sci. Nutr. 64 (2013) 7–15.
[14]M. Rondanelli, A. Riva, G. Petrangolini, P. Allegrini, L. Bernardinelli, T. Fazia, G. Peroni, C. Gasparri, M. Nichetti, M.A. Faliva, M. Naso, S. Perna, Nutrients 12 (2020).
[15]Y. Panahi, P. Kianpour, R. Mohtashami, S.L. Atkin, A.E. Butler, R. Jafari, R. Badeli, A. Sahebkar, Phytother. Res. 32 (2018) 1382–1387.
[16]A. Skarpañska-Stejnborn, L. Pilaczynska-Szczesniak, P. Basta, E. Deskur-Smielecka, M. Horoszkiewicz-Hassan, Int. J. Sport Nutr. Exerc. Metab. 18 (2008) 313–327.
[17]J.E. Brown, C.A. Rice-Evans, Free Radic. Res. 29 (1998) 247–255.
[18]T. Nomikos, P. Detopoulou, E. Fragopoulou, E. Pliakis, S. Antonopoulou, Nutr. Res. 27 (2007) 741–749.
[19]N. Fantini, G. Colombo, A. Giori, A. Riva, P. Morazzoni, E. Bombardelli, M.A.M. Carai, Phytother. Res. 25 (2011) 463–466.
[20]M. Ebrahimi-Mameghani, M. Asghari-Jafarabadi, K. Rezazadeh, J. Integr. Med. 16 (2018) 329–334.
[21]M.-C. Yu, J.-H. Chen, C.-Y. Lai, C.-Y. Han, W.-C. Ko, Eur. J. Pharmacol. 627 (2010) 269–275.